It is necessary to explain the health of body and soul based on Islamic texts. This study examines the physical and mental health of the families living in the village based on the medical teachings of Imam Reza, peace be upon him, in the period of the last six months of 1401 and the first six months of 1402, and by dividing the villagers into two control and experimental groups. have given. The research method is applied in terms of the purpose and in terms of the survey research method and the use of statistical tests, a major part of which is based on field data and completing a questionnaire from the statistical population in the mentioned time period in the villages with a population of more than 1000 people in Zanjan province, which is based on the Kochran sampling formula. A sample of 375 heads of households in the region has been collected and analyzed using physical and mental health indicators obtained according to the experts' opinion and statistical tests of analysis of variance, T-test of paired samples and Pearson's correlation coefficient. The average level of health of the villagers by following the medical teachings of Imam Reza (a.s.) in the last six months of 1401 and after re-examination in the first six months of 1402 in two control and test groups shows that there is a correlation between following the medical teachings and the health of the body and soul. There is a meaningful and positive. The high impact of Imam Reza's medical teachings on the physical and mental health of rural households is obvious. The use of survey studies and quantitative research methods on the effect of the practical use of the medical teachings of Imam Reza (peace be upon him) has been done for the first time.